E | Envelope small membrane protein
 
              DARK BACKGROUND

Hovering over the features in Protvista (below) leads to their highlighting in 3D structure.

Sequence Viewer
Gene
E
Protein Name
Envelope small membrane protein
UniProt ID
P0DTC4 [go to UniProt ] [go to PDBe-KB ]
NCBI Gene ID
43740570
Molecular Weight
8365
Protein Length
75
Protein Domain
InterPro | Pfam
3D Structure
(PDB ID : 7k3g)
PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Catalytic Site
Catalytic Site Atlas
Localization
Host Golgi apparatus membrane;
Function (based on UniProt)
Plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis.

Gene Ontology

ID Name
GO:0039707 pore formation by virus in membrane of host cell
GO:0046760 viral budding from Golgi membrane
ID Name
GO:0044178 host cell Golgi membrane
GO:0016021 integral component of membrane